SizeID.bio
What brings you here?
Foreign Particle Investigation
Found particles? Let’s identify them and investigate their source.
From visible contamination to subvisible particle populations, identify materials, characterize particle distributions and investigate potential contamination sources.
Investigate unknown particles →
Parenteral & Combination Drug Products
Develop your method. Understand your particles.
Develop and validate analytical methods for difficult-to-inspect parenterals. Investigate particle findings and compare populations across development, manufacturing and stability.
Explore parenteral particle analysis
OINDP & MDRS
Comparing formulations? Look beyond particle size alone.
Characterize Raman-confirmed API particles, size distributions and morphology to support test/reference formulation comparisons.
Explore formulation comparability →
Raman identification complements, but does not replace, compendial light obscuration (LO) or microscopic particle-count testing.
Particle evidence throughout the product lifecycle
Develop and validate a suitable method, establish comparable particle profiles and investigate changes as your product and process evolve.
Materials & components
Compare particle profiles from raw materials, containers, closures and process equipment.
Process development & manufacturing
Investigate changes across defined sampling points and process conditions.
Stability & retention samples
Assess changes in particle populations over time.
Ongoing investigations and trending: evaluate recurring findings and changes following corrective actions.
Explore method development and validation
More than particle counts. Evidence that helps you investigate.
Identify
Determine the chemical identity of individual particles using Raman spectroscopy.
Quantify
Characterize particle counts, sizes and material-specific populations.
Compare
Examine differences between samples, batches, components and reference formulations.
Investigate
Combine particle characteristics, reference materials and analytical context to support probable-source investigations.
Optical imaging measures the particle population. Selected particles are measured by Raman to add chemical evidence where the material and sample allow.
Explore automated particle Raman technology →
From a particle image to chemical identity
A particle image shows appearance. Its measured Raman spectrum provides a chemical fingerprint that can be compared with reference materials. In this original example, particle 11292 was identified as polypropylene. Material identity helps focus the investigation; it does not by itself establish the contamination source.
Particle 11292 · Original particle micrograph and associated measured Raman spectrum from the H01 dataset. Raman identification: polypropylene.
View the original image and Raman spectrum at full resolution →
Explore foreign particle identification →
From your question to reviewed findings
We work with you to shape the analytical plan around your question and samples. These steps adapt to the needs of each project.
01
Listen & understand
Discuss the product, samples, existing findings and investigation objectives.
02
Plan the analysis
Agree on suitable methods, sample handling, controls and references.
03
Analyze & interpret
Apply imaging, Raman spectroscopy and relevant particle-population analysis.
04
Report & discuss
Provide documented findings and review their significance with the customer.
Discuss your project →
Reliable analysis. Documented quality.
Documented analytical procedures connect traceable particle images, spectra and results with technical and quality review. Customer audit opportunities support discussion of the documentation relevant to your investigation.
Explore our quality standards →
Let’s discuss your particle investigation.
Tell us about your samples, your analytical challenge and the questions you need to answer. We’ll help you identify a practical next step.
Contact our specialists →